The fonds reflect the activities of the Regina Health District, the Regina District Health Board, and the institutions under the Board's direction: Regina General Hospital, Pasqua Hospital, Plains Health Centre, and Wascana Rehabilitation Centre. Fonds also reflects the activities of the South Saskatchewan Hospital Centre. Fonds consists of correspondence; minutes of the Board of Governors, individual hospitals, departments, committees and the South Saskatchewan Hospital Centre; studies and reports, including consolidation of acute care services, health status and needs assessments, effective hospital care for Regina, Toward 2000 project and functional programs; contracts and agreements; policies, procedures, regulations and guidelines; Medical Staff bylaws; hospital accreditation records; reference materials including articles and newspaper clippings; departmental, institutional and district statistics; financial records; records of construction and renovation (contracts, proposals, architectural drawings, correspondence, reports and photographs), including the Regina Hospitals Regeneration Program and renovation of the Allan Blair Memorial Clinic; staff records, including labour relations records, biographies and photographs of physicians, labour contracts, conference files; disaster plans; subject files; manuals and directories; hospital accreditation records; surveys and questionnaires; annual reports; news releases; and telephone directories.

Fonds also documents the relationship between the Regina Health District and the following external agencies and associations: Canadian College of Health Service Executives; Saskatchewan Association of Health Services Executives; Health Services Utilization Resources Council (Saskatchewan); Saskatchewan Association of Health Organizations (SAHO); Saskatchewan Health; Saskatoon Health District; College of Physicians and Surgeons of Saskatchewan; College of Medicine, University of Saskatchewan; Professional Association of Internes and Residents of Saskatchewan; Human Rights Commission; Labour Relations Board; Saskatchewan Labour Relations Symposium; Human Resource Management Association; Canadian Union of Public Employees (CUPE), Locals 176 (Regina General Hospital), 1612 (Pasqua Hospital) and 1838 (Plains Health Centre); Saskatchewan Council of Human Resource Associations; Saskatchewan Government and General Employees Union; Saskatchewan Public Service Commission; Saskatchewan Union of Nurses (SUN); Saskatchewan Registered Nurses Association (SRNA); Victorian Order of Nurses; Allan Blair Memorial Clinic; Saskatchewan Cancer Foundation; University of Regina; Saskatchewan Institute of Applied Science and Technology; Hospitals of Regina Foundation; City of Regina; and the United Way.