The fonds consists of: Correspondence; minutes of departments and committees; studies and reports, including bed allocation, "Beds Needs Study and Functional Program for Emergency and Critical Care Services" (Atkinson report), space evaluation, hospital waiting list, nuclear medicine services in Regina and teaching accreditation survey; agreements, including the Hospital of Regina Foundation sharing agreement, affiliation agreement between the University of Saskatchewan and Regina Teaching Hospitals, and medical office agreements; institutional by-laws, policies and procedures, rules and regulations; reference materials, including articles, bulletins, pamphlets and reports; surveys and questionnaires; statistics; financial records, personnel and labour relations records, photographs of Plains Health Centre people, buildings and events; conference files; patient education material for diabetes; disaster plans; subject files; hospital accreditation records; records of construction and renovation; manuals; records of donations, bequests and fundraising; and records of quality assurance.

Fonds documents the relationship between the Plains Health Centre and the following external departments, agencies and associations: Canadian Cancer Society; Allan Blair Memorial Clinic; Provincial Laboratory Services; Saskatchewan Healthcare Associations; College of Physicians and Surgeons of Saskatchewan; Canadian Medical Association; Saskatchewan Medical Association; College of Medicine, University of Saskatchewan; Canadian Hospital Association; Saskatchewan Association of Health Service Executives; Saskatchewan Council of Teaching Hospitals; Canadian Union of Public Employees; Professional Association of Internes and Residents of Saskatchewan; Saskatchewan Union of Nurses; Saskatchewan Registered Nurses Association; Hospitals of Regina Foundation; Kinsmen Foundation Inc.; Saskatchewan Heart Foundation; Saskatchewan Lung Association; United Way Campaign; and XZ Service Club of Regina [Zonta International Club]. Fonds also documents the South Saskatchewan Hospital Centre Board and the Regina District Health Board.