Regina Metropolitan Pastoral Charge was formed as a new United Church charge in 1925, containing the preaching point Metropolitan United Church, formerly Metropolitan Methodist Church.

In 1951, Knox United Church amalgamated with Metropolitan United Church, to become Knox-Metropolitan United Church (and Pastoral Charge), located on the site of the former Metropolitan United Church, at the corner of Victoria Avenue and Lorne Street.

Knox-Metropolitan Pastoral Charge was formed after the Knox and Metropolitan United Church congregations amalgamated to form Knox-Metropolitan United Church, on the site of the (former) Metropolitan United Church, at the corner of Victoria Avenue and Lorne Street.

Regina Knox Pastoral Charge was formed as a new United Church charge in 1925, containing the preaching point Knox United Church, formerly Knox Presbyterian Church. The previous Presbyterian congregation dated back to around 1882. It built a church in 1885, at the corner of Scarth Street and 11th Avenue, and a later replacement in 1905.

In 1951, Knox United Church amalgamated with Metropolitan United Church, to become Knox-Metropolitan United Church (and Pastoral Charge), located on the site of the former Metropolitan United Church, at the corner of Victoria Avenue and Lorne Street.

Regina Heritage Pastoral Charge was established January 1, 1984, from a preaching point previously part of Regina St. James Pastoral Charge.

Regina Eastside Pastoral Charge was created as Prince of Peace Pastoral Charge (from the main preaching point), a new church development, on September 6, 1987. On January 1, 1998, the charge was renamed Eastside Pastoral Charge.

Regina Chalmers Pastoral Charge was formed as a new United Church charge in 1925, from what had previously been a Presbyterian field. Around 1932, it consisted of Chalmers, Rosemont and St. James congregations but these were reorganized by 1936, with Chalmers listed as under Settlement House, until the early 1940s. The Pastoral Charge was later re-established ca.1946 and eventually closed, June 30, 1994.

Regina Carmichael Pastoral Charge was formed as a new United Church charge in 1925, containing the Carmichael United Church preaching point. The church had been originally formed (in 1925) by congregations at the former Wesley Methodist Church and Carmichael Presbyterian Church, named after a former Presbyterian Superintendent of Missions, Dr. James Carmichael. The charge closed June 30, 1995.

Redvers Pastoral Charge was formed as a new United Church charge in 1925, part of Arcola Presbytery and containing the preaching points at Redvers, Hutton and Silvervale. By 1932, an appointment at Mair had been added and, by 1936, Silvervale was removed. As of 1940, Annandale was also part of the charge but only Redvers and Mair remained by 1946. In 1951, the charge consisted of Redvers, Storthoaks and Thunder Creek.

Around 1962, Redvers amalgamated with Antler Pastoral Charge to form Antler-Redvers Pastoral Charge, with points at Antler, Redvers, and Sinclair (Manitoba). This continued until ca.1977, when the church at Manor joined the charge and it returned to the name Redvers Pastoral Charge. Antler officially closed June 30, 1992, leaving only Redvers and Manor. On June 30, 2002, the charge became a shared ministry. Manor (Knox United Church) left the charge on July 1, 2015, and re-formed Manor United Pastoral Charge.

Davis Pastoral Charge (later Red Deer Hill Pastoral Charge) was formed as a new aid-receiving United Church charge ca.1926, part of Prince Albert Presbytery and consisting of appointments at Davis, Red Deer Hill, Deer Park and Meridian. By 1932, only Davis and Red Deer Hill were still listed as part of the charge. As of 1951, the charge was being served by a student minister and Russelville was included. In the late-1950s, the charge was joined with Colleston Pastoral Charge, though the two were separate again by 1959 and Davis Pastoral Charge was served by retired supply ministry (D.G. Rice). As of 1963, Davis was no longer listed as a preaching point, leaving only Red Deer Hill as the Pastoral Charge, served by a student minster. On April 1, 2004, Red Deer Hill Pastoral Charge was officially closed.

Qu'Appelle Pastoral Charge was formed as a new United Church charge in 1925, part of Qu'Appelle Presbytery and consisting of appointments at Qu'Appelle and Edgeley. The congregation at Qu'Appelle can be traced to Presbyterian and Methodist congregations from at least the 1880s, which joined in 1925, creating Knox United Church, in the former Presbyterian building (built ca.1907, replacing a previous 1886 building). The Methodist Qu'Appelle Circuit (formed ca.1882) had served congregations in Qu'Appelle and Edgeley, both of which also built churches, in 1883.

By 1962, Qu'Appelle Pastoral Charge points at Qu'Appelle and Edgeley had been joined by McLean and Avonhurst (formerly McLean Pastoral Charge). By 1969, Avonhurst was no longer listed in the charge. On April 1, 1989, Edgeley and McLean separated and formed their own pastoral charges. In 2018, the remaining Qu'Appelle Knox Pastoral Charge was disbanded. (The separate Edgeley Pastoral Charge continued on.)