Melfort Pastoral Charge was formed as a new United Church charge in 1925, containing the preaching points at Melfort and Beatty. On July 1, 1995, the charge became part of a new Melfort-Ethelton Pastoral Charge, after the division of the former Kinistino-Ethelton Pastoral Charge (other points became part of Birch Hills - Kinistino Pastoral Charge). Ethelton United Church closed November 15, 2011.

Melville Pastoral Charge was formed as a new United Church charge in 1925, containing First United Church, in Melville. This congregation is generally considered the first Local Union formed in Canada, dating back to 1908 and coinciding with the Basis of Union, which eventually lead to the creation of the United Church of Canada. Original members included Methodists, Baptists, Congregationalists, and Presbyterians.

Regina Carmichael Pastoral Charge was formed as a new United Church charge in 1925, containing the Carmichael United Church preaching point. The church had been originally formed (in 1925) by congregations at the former Wesley Methodist Church and Carmichael Presbyterian Church, named after a former Presbyterian Superintendent of Missions, Dr. James Carmichael. The charge closed June 30, 1995.

Regina Metropolitan Pastoral Charge was formed as a new United Church charge in 1925, containing the preaching point Metropolitan United Church, formerly Metropolitan Methodist Church.

In 1951, Knox United Church amalgamated with Metropolitan United Church, to become Knox-Metropolitan United Church (and Pastoral Charge), located on the site of the former Metropolitan United Church, at the corner of Victoria Avenue and Lorne Street.

Star City Pastoral Charge was formed as a new United Church charge in 1925, part of Prince Albert Presbytery and containing Star City, Campbellville, and Valparaiso appointments. By 1951, only Star City and Valparaiso remained in the charge. Brooksby was later added (before 1962) and Valparaiso removed (ca.1965).

Tugaske Pastoral Charge was formed as a new United Church charge in 1925, part of Moose Jaw Presbytery and containing just the Tugaske preaching point.

Between 1946 and 1951, Tugaske and Eybrow Pastoral Charges amalgamated to form Tugaske-Eyebrow Pastoral Charge, with appointments at Bridgeford, Brownlee, Eskbank, Eyebrow, and Tugaske. Lake Valley was added around 1965 and Keeler around 1982. Brownlee amalgamated with Keeler in 1986 and eventually closed, on June 30, 1996.

The charge amalgamated with Central Butte Pastoral Charge, on July 1, 2007, forming the new Spirit Hills Pastoral Charge.

Weyburn Pastoral Charge was formed as a new self-sustaining United Church charge in 1925, part of Weyburn Presbytery.

Foxdale Pastoral Charge was formed around 1926, as an aid-receiving United Church charge, part of Prince Albert Presbytery. By 1932, the charge included Foxdale, Canwood, Silver Cliff and Sturgeon River points, and was listed as Canwood-Foxdale Pastoral Charge. As of 1936, the name had shifted to Canwood Pastoral Charge and it consisted of just Canwood, Polwarth and Silver Cliff. Marchant Grove was added and Silver Cliff removed by 1940. Sometime between 1946 and 1951, the points moved into Shellbrook Pastoral Charge.

Around 1972, Canwood moved from Shellbrook Pastoral Charge (which became Shellbrook-Leask) to Big River Pastoral Charge, which was re-named Big River - Canwood Pastoral Charge. Canwood's Trinity United Church closed March 30 2010, leaving just Big River's First United Church and the charge would return to the name Big River Pastoral Charge.

Maple Creek Pastoral Charge was formed as a new United Church charge in 1925, containing preaching points at Maple Creek and Motherwell.